TORIPALIMAB IN AN ADVANCED NON-SMALL CELL LUNG CANCER PATIENT WITH POOR GENERAL CONDITION AFTER MULTILINE TREATMENT: A CASE REPORT

Toripalimab in an advanced non-small cell lung cancer patient with poor general condition after multiline treatment: a case report

Several clinical trials have proven that immunotherapy can improve survival and benefit non-small cell lung cancer (NSCLC) patients.In patients who progress after chemotherapy, immune checkpoint inhibitor (ICI) monotherapy can prolong overall survival compared with patients receiving single-agent chemotherapy.A 61-year-old man diagnosed with advanc

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Proteins with complex architecture as potential targets for drug design: a case study of Mycobacterium tuberculosis.

Lengthy co-evolution of Homo sapiens and Mycobacterium tuberculosis, the main causative agent of Baseball tuberculosis, resulted in a dramatically successful pathogen species that presents considerable challenge for modern medicine.The continuous and ever increasing appearance of multi-drug resistant mycobacteria necessitates the identification of

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Existence and uniqueness of the solution of the coupled conduction-radiation energy transfer on diffuse-gray surfaces

This article gives very significant and up-to-date analytical results on the conductive-radiative heat transfer model containing two conducting and opaque materials which are in contact by radiation through a transparent medium bounded by diffuse-gray surfaces.Some properties of the radiative integral operator will be presented.The main emphasis Po

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Analytical modeling of cross-ply cylindrical composite submersible shell with elastic buckling using first order shear deformation theory

The main objective of this study is to design composite shells i.e.long, short, thin and thick for the different underwater applications.These shells can be a part of pressure hulls, underwater vehicles, pressurized Toslink tanks, underwater cables and underwater pipelines etc.This paper presents comprehensive procedures for the mathematical modeli

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